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Article

[Research progress on genes mutations related to sulfa drug resistance in Pneumocystis jirovecii].

Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences - 25 May 2017

Wang Mengyan, Zhu Biao

Abstract excerpt

Pneumocystis jirovecii pneumonia is an opportunistic infection among immunocompromised people. Studies have found that the increased resistance to sulfa drugs of Pneumocystis jirovecii may be associated with the mutation of dihydropteroate synthase (DHPS) gene and dihydrofolate reductase (DHFR) genes, but the mechanism is still unclear. The mutation of DHPS and DHFR genes may be the result of sulfa drugs...

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Source

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Identifiers

PMID: 29488726
DOI: 10.3785/j.issn.1008-9292.2017.10.18
PMCID: PMC10397033

Genes

DHFR
DHPS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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