Article
Effect of adenosine monophosphate deaminase-1 C34T allele on the requirement for donor inotropic support and on the incidence of early graft dysfunction after cardiac transplantation.
The American journal of cardiology - 15 May 2009
Taegtmeyer Anne B, Breen Jane B, Rogers Paula, Johnson Philip H, Smith John, Smolenski Ryzard T, Banner Nicholas R, Yacoub Magdi H, Barton Paul J
Abstract excerpt
The C34T T allele of the adenosine monophosphate deaminase-1 (AMPD1) gene has been associated with improved outcome in patients with cardiac dysfunction. We hypothesized that possession of this allele by donor hearts plays a role in the outcome of cardiac transplantation; 262 cardiac donors and 190 of their recipients were studied. AMPD1 C34T genotype was determined using 5' exonuclease chemistry. Requirement for...
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