Article
The impact of the AMPD1 gene polymorphism on exercise capacity, other prognostic parameters, and survival in patients with stable congestive heart failure: a study in 686 consecutive patients.
American heart journal - 1 Oct 2006
de Groote Pascal, Lamblin Nicolas, Helbecque Nicole, Mouquet Frédéric, Hermant Xavier, Amouyel Philippe, Dallongeville Jean, Bauters Christophe
Abstract excerpt
BACKGROUND: Previous studies have demonstrated that the adenosine monophosphate deaminase 1 (AMPD1) C34T polymorphism may be associated with survival in cardiac populations with a protective effect of the T allele. However, these studies included limited number of patients with few cardiovascular events. METHODS: We prospectively analyzed the impact of the C34T polymorphism of the AMPD1 gene in 686 unrelated...
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