Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Common variant in AMPD1 gene predicts improved clinical outcome in patients with heart failure.

Circulation - 23 Mar 1999

Loh E, Rebbeck T R, Mahoney P D, DeNofrio D, Swain J L, Holmes E W

Abstract excerpt

BACKGROUND: This study was undertaken to identify gene(s) that may be associated with improved clinical outcome in patients with congestive heart failure (CHF). The adenosine monophosphate deaminase locus (AMPD1) was selected for study. We hypothesized that inheritance of the mutant AMPD1 allele is associated with increased probability of survival without cardiac transplantation in patients with CHF. METHODS AND...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine Monophosphate
Share to AMP Deaminase
Share to Angiotensin-Converting Enzyme Inhibitors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cardiomyopathy, Dilated

Share to Digoxin

Share to Diuretics

Share to Hemodynamics

Share to Oxygen Consumption

Source

Identifiers

PMID: 10086964
DOI: 10.1161/01.cir.99.11.1422

Genes

AMPD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Common variant in AMPD1 gene predicts improved clinical outcome in patients with heart failure.PMID 10086964Read ↗

A common variant of the AMPD1 gene predicts improved cardiovascular survival in patients with coronary artery disease.Semantic proximity Read ↗

A common variant of the AMPD1 gene predicts improved survival in patients with ischemic left ventricular dysfunction.Semantic proximity Read ↗

AMP deaminase 1 gene polymorphism and heart disease-a genetic association that highlights new treatment.Semantic proximity Read ↗

The role of a common adenosine monophosphate deaminase (AMPD)-1 polymorphism in outcomes of ischemic and nonischemic heart failure.Semantic proximity Read ↗

The impact of the AMPD1 gene polymorphism on exercise capacity, other prognostic parameters, and survival in patients with stable congestive heart failure: a study in 686 consecutive patients.Semantic proximity Read ↗

C34T AMP deaminase 1 gene mutation protects cardiac function in donors.Semantic proximity Read ↗

Decreased cardiac activity of AMP deaminase in subjects with the AMPD1 mutation--a potential mechanism of protection in heart failure.Semantic proximity Read ↗

AMPD1 (C34T) polymorphism and clinical outcomes in patients undergoing myocardial revascularization.Semantic proximity Read ↗

Effect of adenosine monophosphate deaminase-1 C34T allele on the requirement for donor inotropic support and on the incidence of early graft dysfunction after cardiac transplantation.Semantic proximity Read ↗

Evaluation of AMPD1 C34T genotype as a predictor of mortality in heart failure and post-myocardial infarction patients.Semantic proximity Read ↗

Association of C34T AMPD1 gene polymorphism with features of metabolic syndrome in patients with coronary artery disease or heart failure.Semantic proximity Read ↗

Association of improved cardiac function in donors with C34T mutation of the AMP deaminase 1 gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.