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Article

A common variant of the AMPD1 gene predicts improved cardiovascular survival in patients with coronary artery disease.

Journal of the American College of Cardiology - 1 Oct 2000

Anderson J L, Habashi J, Carlquist J F, Muhlestein J B, Horne B D, Bair T L, Pearson R R, Hart N

Abstract excerpt

OBJECTIVE: We tested whether a common AMPD1 gene variant is associated with improved cardiovascular (CV) survival in patients with coronary artery disease (CAD). BACKGROUND: Reduced activity of adenosine monophosphate deaminase (AMPD) may increase production of adenosine, a cardioprotective agent. A common, nonsense, point variant of the AMPD1 gene (C34T) results in enzymatic inactivity and has been associated...

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Source

Identifiers

PMID: 11028479
DOI: 10.1016/s0735-1097(00)00850-0

Genes

AMPD1
CAD

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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