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Article

A common variant of the AMPD1 gene predicts improved survival in patients with ischemic left ventricular dysfunction.

Journal of cardiac failure - 1 Aug 2004

Yazaki Yoshikazu, Muhlestein Joseph B, Carlquist John F, Bair Tami L, Horne Benjamin D, Renlund Dale G, Anderson Jeffrey L

Abstract excerpt

BACKGROUND: A recent retrospective study suggested that the adenosine monophosphate deaminase (AMPD)-1 gene variant C34T predicts outcome in heart failure patients. This variant might lead to ischemic preconditioning by increasing tissue adenosine. We tested whether the survival benefit of C34T occurs preferentially in the setting of ischemic left ventricular dysfunction. METHODS AND RESULTS: A consecutive cohort...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15309698
DOI: 10.1016/j.cardfail.2003.10.008

Genes

AMPD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A common variant of the AMPD1 gene predicts improved survival in patients with ischemic left ventricular dysfunction.PMID 15309698Read ↗

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A common variant of the AMPD1 gene predicts improved cardiovascular survival in patients with coronary artery disease.Semantic proximity Read ↗

Common variant in AMPD1 gene predicts improved clinical outcome in patients with heart failure.Semantic proximity Read ↗

Evaluation of AMPD1 C34T genotype as a predictor of mortality in heart failure and post-myocardial infarction patients.Semantic proximity Read ↗

AMP deaminase 1 gene polymorphism and heart disease-a genetic association that highlights new treatment.Semantic proximity Read ↗

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