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Article

The role of a common adenosine monophosphate deaminase (AMPD)-1 polymorphism in outcomes of ischemic and nonischemic heart failure.

Journal of cardiac failure - 1 Dec 2005

Kolek Matthew J, Carlquist John F, Thaneemit-Chen Surai, Lazzeroni Laura C, Whiting Bryant M, Horne Benjamin D, Muhlestein Joseph B, Lavori Philip, Anderson Jeffrey L

Abstract excerpt

BACKGROUND: A common variant of the adenosine monophosphate deaminase (AMPD)-1 gene (C34T) results in enzymatic inactivity and may increase adenosine in cardiac muscle and confer cardioprotection through ischemic preconditioning. METHODS AND RESULTS: We hypothesized that AMPD1 carriers with ischemic heart failure (HF) in the Beta-Blocker Evaluation of Survival Trial (BEST) might have a relative survival...

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Source

Identifiers

PMID: 16360962
DOI: 10.1016/j.cardfail.2005.06.437

Genes

AMPD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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The role of a common adenosine monophosphate deaminase (AMPD)-1 polymorphism in outcomes of ischemic and nonischemic heart failure.PMID 16360962Read ↗

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AMP deaminase 1 gene polymorphism and heart disease-a genetic association that highlights new treatment.Semantic proximity Read ↗

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