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Study of thyroid hormone receptor alpha gene polymorphisms on Alzheimer's disease.

Neurobiology of aging - 1 Apr 2011

Goumidi Louisa, Flamant Frédéric, Lendon Corinne, Galimberti Daniela, Pasquier Florence, Scarpini Elio, Hannequin Didier, Campion Dominique, Amouyel Philippe, Lambert Jean-Charles, Meirhaeghe Aline

Abstract excerpt

Because the action of thyroid hormone (T3) is involved in adult cognitive functions, we wanted to assess the association between THRA gene polymorphisms, which encodes the T3 nuclear receptor TRα1, and Alzheimer's disease (AD) risk. We analysed 5 single nucleotide polymorphisms (SNPs) of THRA, covering the known common genetic variability of the gene, in the Lille AD case-control study (710 cases/597 controls)....

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PMID: 19427062
DOI: 10.1016/j.neurobiolaging.2009.04.007

Genes

THRA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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