Article
Alpha 1-antichymotrypsin gene polymorphism and risk for Alzheimer's disease.
Journal of neural transmission (Vienna, Austria : 1996) - 1 Jan 1996
Muramatsu T, Matsushita S, Arai H, Sasaki H, Higuchi S
Abstract excerpt
alpha 1-Antichymotrypsin (ACT), a component of the senile plaque of the Alzheimer's disease (AD) brain, has a possible role as a molecular chaperone in developing AD pathology. This study was a search for the possible association of the two structural polymorphisms of ACT, Ala15-->Thr and Met389-...
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