Article
Common variants of human TERT and TERC genes and susceptibility to sporadic Alzheimers disease.
Experimental gerontology - 1 Feb 2017
Scarabino D, Broggio E, Gambina G, Pelliccia F, Corbo R M
Abstract excerpt
Studies investigating telomere length in association with cognitive decline, dementia, and sporadic Alzheimer's disease (AD) have frequently found shorter telomeres to be associated with the development of AD and telomerase expression with pathological processes in AD. Human telomerase is constituted by two components: the telomerase reverse transcriptase (TERT) and the telomerase RNA component (TERC). Genetic...
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