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Article

Association between Alzheimer disease and the -491T allele of regulatory region polymorphism of Apolipoprotein E in a Tunisian population.

Neurochemical research - 1 Feb 2014

Achouri-Rassas Afef, Hadj Fredj Sondes, Mrabet Khiari Hela, Bibi Amina, Siala Hajer, Mrabet Amel, Messaoud Taieb

Abstract excerpt

The apolipoprotein E (APOE) is a well-established risk factor for late-onset Alzheimer's disease (AD). Several studies have attempted to confirm the association between the polymorphism located at position -491 in the transcriptional regulatory region of the APOE gene and AD. We examined in 85 AD patients and 90 control subjects of a Tunisian population the potential involvement of this polymorphism as a risk...

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Identifiers

PMID: 24326531
DOI: 10.1007/s11064-013-1213-y

Genes

APOE

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