Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

14-3-3 zeta and tau genes interactively decrease Alzheimer's disease risk.

Dementia and geriatric cognitive disorders - 1 Jan 2008

Mateo Ignacio, Sánchez-Juan Pascual, Rodríguez-Rodríguez Eloy, Infante Jon, Fernández-Viadero Carlos, Peña Nicolás, Berciano José, Combarros Onofre

Abstract excerpt

Abnormal tau hyperphosphorylation has been suggested as being one of the central events in the development of neurofibrillary tangles, which are one of the characteristic neuropathological lesions found in Alzheimer's disease (AD) brains. 14-3-3 zeta protein is associated with tau in brain and st...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 14-3-3 Proteins
Share to Aged, 80 and over
Share to Alzheimer Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Apolipoprotein E4

Share to Introns

Share to Odds Ratio

Share to Phosphorylation

Share to tau Proteins

Source

Identifiers

PMID: 18319590
DOI: 10.1159/000119123

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18319590-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

14-3-3 zeta and tau genes interactively decrease Alzheimer's disease risk.PMID 18319590Read ↗

Gene-gene interaction between 14-3-3 zeta and butyrylcholinesterase modulates Alzheimer's disease risk.Semantic proximity Read ↗

Genetic interaction between tau and the apolipoprotein E receptor LRP1 Increases Alzheimer's disease risk.Semantic proximity Read ↗

GSK3B polymorphisms alter transcription and splicing in Parkinson's disease.Semantic proximity Read ↗

Synergistic effect of heme oxygenase-1 and tau genetic variants on Alzheimer's disease risk.Semantic proximity Read ↗

Genetic association between PLTP gene polymorphisms and Alzheimer's disease in a Japanese population.Semantic proximity Read ↗

Synergistic effect of two oxidative stress-related genes (heme oxygenase-1 and GSK3β) on the risk of Parkinson's disease.Semantic proximity Read ↗

Glutathione S-transferase theta genetic polymorphism might influence tacrine hepatotoxicity in Alzheimer's patients.Semantic proximity Read ↗

Possible association of missense mutation (Gly[-63]Glu) of the neurotrophin-3 gene with Alzheimer's disease in Japanese.Semantic proximity Read ↗

Study of thyroid hormone receptor alpha gene polymorphisms on Alzheimer's disease.Semantic proximity Read ↗

Association of tau gene polymorphism with Parkinson's disease.Semantic proximity Read ↗

Polymorphisms of the neurotrophic factor-3 (NTF-3) in Alzheimer's disease: rs6332 associated with onset time and rs6489630 T allele exhibited a protective role.Semantic proximity Read ↗

Genetic analysis of tumor necrosis factor-alpha (TNF-alpha) G-308A and Saitohin Q7R polymorphisms with Alzheimer's disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.