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Article

The zebrafish nrc mutant reveals a role for the polyphosphoinositide phosphatase synaptojanin 1 in cone photoreceptor ribbon anchoring.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 6 Oct 2004

Van Epps Heather A, Hayashi Mitsuko, Lucast Louise, Stearns George W, Hurley James B, De Camilli Pietro, Brockerhoff Susan E

Abstract excerpt

Visual, vestibular, and auditory neurons rely on ribbon synapses for rapid continuous release and recycling of synaptic vesicles. Molecular mechanisms responsible for the properties of ribbon synapses are mostly unknown. The zebrafish vision mutant nrc has unanchored ribbons and abnormal synaptic transmission at cone photoreceptor synapses. We used positional cloning to identify the nrc mutation as a premature...

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Identifiers

PMID: 15470129
DOI: 10.1523/JNEUROSCI.2892-04.2004
PMCID: PMC6729946

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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