Variation in CHI3LI in relation to type 2 diabetes and related quantitative traits.

doi:10.1371/journal.pone.0005469

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Variation in CHI3LI in relation to type 2 diabetes and related quantitative traits.

PloS one - 1 Jan 2009

Rathcke Camilla Noelle, Holmkvist Johan, Jørgensen Torben, Borch-Johnsen Knut, Hansen Torben, Pedersen Oluf Borbye, Vestergaard Henrik

Abstract excerpt

BACKGROUND: CHI3LI encoding the inflammatory glycoprotein YKL-40 is located on chromosome 1q32.1. YKL-40 is involved in inflammatory processes and patients with Type 2 Diabetes (T2D) have elevated circulating YKL-40 levels which correlate with their level of insulin resistance. Interestingly, it has been reported that rs10399931 (-329 G/A) of CHI3LI contributes to the inter-individual plasma YKL-40 levels in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipokines

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chitinase-3-Like Protein 1

Share to Diabetes Mellitus, Type 2

Share to Glucose Tolerance Test

Share to Glycoproteins

Share to Insulin Resistance

Share to Lectins

Share to Quantitative Trait Loci

Source

Open in PubMed Open full text

Identifiers

PMID: 19421404
DOI: 10.1371/journal.pone.0005469
PMCID: PMC2674946

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Variation in CHI3LI in relation to type 2 diabetes and related quantitative traits.PMID 19421404Read ↗

The Association between genetic variations of CHI3L1, levels of the encoded glycoprotein YKL-40 and the lipid profile in a Danish population.Semantic proximity Read ↗

Variations of CHI3L1, levels of the encoded glycoprotein YKL-40 and prediction of fatal and non-fatal ischemic stroke.Semantic proximity Read ↗

Circulating YKL-40 level, but not CHI3L1 gene variants, is associated with atherosclerosis-related quantitative traits and the risk of peripheral artery disease.Semantic proximity Read ↗

Association of CHI3L1 gene variants with YKL-40 levels and hypertension incidence: A population-based nested case-control study in China.Semantic proximity Read ↗

Associations of the Inflammatory Marker YKL-40 with Measures of Obesity and Dyslipidaemia in Individuals at High Risk of Type 2 Diabetes.Semantic proximity Read ↗

Genetic variability of GCKR alters lipid profiles in children with monogenic and autoimmune diabetes.Semantic proximity Read ↗

[Association between CHI3L1 SNPs and susceptibility to childhood asthma].Semantic proximity Read ↗

Association of polymorphisms of the CHI3L1 gene with asthma and atopy: a populations-based study of 6514 Danish adults.Semantic proximity Read ↗

YKL-40 as a clinical biomarker in adult patients with CF: Implications of a CHI3L1 single nucleotide polymorphism in disease severity.Semantic proximity Read ↗

Genetic and epigenetic regulation of YKL-40 in childhood.Semantic proximity Read ↗

NEUROG3 variants and type 2 diabetes in Italians.Semantic proximity Read ↗

A CHI3L1 gene polymorphism is associated with serum levels of YKL-40, a novel sarcoidosis marker.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.