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Article

Circulating YKL-40 level, but not CHI3L1 gene variants, is associated with atherosclerosis-related quantitative traits and the risk of peripheral artery disease.

International journal of molecular sciences - 4 Dec 2014

Wu Semon, Hsu Lung-An, Cheng Shih-Tsung, Teng Ming-Sheng, Yeh Ching-Hua, Sun Yu-Chen, Huang Hsuan-Li, Ko Yu-Lin

Abstract excerpt

YKL-40, a pleotropic cytokine, is emerging as a risk factor and a prognostic predictor of atherosclerotic cardiovascular disease. We attempted to elucidate the genetic, clinical and biochemical correlates of circulating YKL-40 level and, by combining it with CHI3L1 gene variants, with the risk and long-term mortality of peripheral artery disease (PAD). Plasma YKL-40 concentrations were measured in 612 Taiwanese...

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Identifiers

PMID: 25486056
DOI: 10.3390/ijms151222421
PMCID: PMC4284717

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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