Article
A CHI3L1 gene polymorphism is associated with serum levels of YKL-40, a novel sarcoidosis marker.
Respiratory medicine - 1 Jul 2007
Kruit Adrian, Grutters Jan C, Ruven Henk J T, van Moorsel Coline C M, van den Bosch Jules M M
Abstract excerpt
BACKGROUND: YKL-40, a chitinase-like cartilage glycoprotein, has recently shown its potential as a marker for sarcoidosis. METHODS: This study aimed to assess whether YKL-40 at presentation may predict the course of sarcoidosis over a 4-year follow-up period and to investigate whether polymorphisms in the chitinase 3-like 1 (CHI3L1) gene might influence serum YKL-40 levels in sarcoidosis patients (n=63) and...
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