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Article

Photostimulation of retrotrapezoid nucleus phox2b-expressing neurons in vivo produces long-lasting activation of breathing in rats.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 6 May 2009

Abbott Stephen B G, Stornetta Ruth L, Fortuna Michal G, Depuy Seth D, West Gavin H, Harris Thurl E, Guyenet Patrice G

Abstract excerpt

The retrotrapezoid "nucleus" (RTN), located in the rostral ventrolateral medullary reticular formation, contains a bilateral cluster of approximately 1000 glutamatergic noncatecholaminergic Phox2b-expressing propriobulbar neurons that are activated by CO(2) in vivo and by acidification in vitro. These cells are thought to function as central respiratory chemoreceptors, but this theory still lacks a crucial piece...

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Identifiers

PMID: 19420248
DOI: 10.1523/JNEUROSCI.1106-09.2009
PMCID: PMC2696034

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Photostimulation of retrotrapezoid nucleus phox2b-expressing neurons in vivo produces long-lasting activation of breathing in rats.PMID 19420248Read ↗

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