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Article

Characterization of sulfoxygenation and structural implications of human flavin-containing monooxygenase isoform 2 (FMO2.1) variants S195L and N413K.

Drug metabolism and disposition: the biological fate of chemicals - 1 Aug 2009

Krueger Sharon K, Henderson Marilyn C, Siddens Lisbeth K, VanDyke Jonathan E, Benninghoff Abby D, Karplus P Andrew, Furnes Bjarte, Schlenk Daniel, Williams David E

Abstract excerpt

Catalytically active human flavin-containing monooxygenase isoform 2 (FMO2.1) is encoded by an allele detected only in individuals of African or Hispanic origin. Genotyping and haplotyping studies indicate that S195L and N413K occasionally occur secondary to the functional FMO2*1 allele encoding...

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Identifiers

PMID: 19420133
DOI: 10.1124/dmd.109.027201
PMCID: PMC2712441

Genes

FMO2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19420133-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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