Article
Phosphodiesterase 4D and 5-lipoxygenase activating protein genes and risk of ischemic stroke in Sardinians.
European journal of human genetics : EJHG - 1 Nov 2009
Quarta Giovanni, Stanzione Rosita, Evangelista Anna, Zanda Bastianina, Di Angelantonio Emanuele, Marchitti Simona, Di Castro Sara, Di Vavo Marta, Volpe Massimo, Rubattu Speranza
Abstract excerpt
Genetic factors contribute to the risk of ischemic stroke (IS). The phosphodiesterase-4D (PDE4D) and the 5-lipoxygenase activating protein (ALOX5AP) genes were identified as contributors to stroke in an Icelandic population. In an attempt to better define the contributory role of PDE4D and ALOX5AP genes to the risk of IS in humans, we carried out the present association study in a well-characterized, earlier...
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