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Article

PDE4D and ALOX5AP genetic variants and risk for Ischemic Cerebrovascular Disease in Sweden.

Journal of the neurological sciences - 15 Dec 2007

Kostulas Konstantinos, Gretarsdottir Solveig, Kostulas Vasilios, Manolescu Andrei, Helgadottir Anna, Thorleifsson Gudmar, Gudmundsson Larus J, Thorsteinsdottir Unnur, Gulcher Jeffrey R, Stefansson Kari, Hillert Jan

Abstract excerpt

BACKGROUND: Genetic variants in Phosphodiesterase 4D (PDE4D) and 5-lipoxygenase activating protein (ALOX5AP) have been shown to confer risk of Ischemic Cerebrovascular Disease (ICVD) in Iceland. We investigated whether these variants associate with ICVD in Sweden. METHODS: Previously published PDE4D and ALOX5AP gene variants were genotyped for cases (685) and controls (751). In PDE4D this consisted of SNP41,...

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PMID: 17655870
DOI: 10.1016/j.jns.2007.06.042

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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