Article
Evaluation of single nucleotide polymorphisms in the phosphodiesterase 4D gene (PDE4D) and their association with ischaemic stroke in a large German cohort.
Journal of neurology, neurosurgery, and psychiatry - 1 Apr 2006
Kuhlenbäumer G, Berger K, Huge A, Lange E, Kessler C, John U, Funke H, Nabavi D G, Stögbauer F, Ringelstein E B, Stoll M
Abstract excerpt
Genetic fine mapping of the first locus identified for genetically complex forms of stroke, STRK1 (which has been mapped to chromosome 5q12 in Icelandic families), has identified the phosphodiesterase 4D gene (PDE4D) gene as a good candidate gene. Association analysis of single nucleotide polymorphisms (SNPs) in the PDE4D gene in an Icelandic stroke cohort demonstrated genetic association between six SNPs in the...
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