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Article

Ischaemic stroke in hypertensive patients is associated with variations in the PDE4D genome region.

European journal of human genetics : EJHG - 1 Sept 2008

Lövkvist Håkan, Smith Jan Gustav, Luthman Holger, Höglund Peter, Norrving Bo, Kristoffersson Ulf, Jönsson Ann-Cathrin, Lindgren Arne G

Abstract excerpt

Previous Icelandic studies reported that single nucleotide polymorphisms (SNPs) in the phosphodiesterase 4D (PDE4D) region and the 5-lipoxygenase activating protein ALOX5AP were associated with ischaemic stroke, whereas other studies reported ambiguous findings. We examined 932 ischaemic stroke patients from a Swedish population-based stroke register, and 396 control subjects. We assessed possible associations...

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Identifiers

PMID: 18398440
DOI: 10.1038/ejhg.2008.62

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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