Article
Early white‐matter abnormalities of the ventral frontostriatal pathway in fragile X syndrome
24 Mar 2009
Abstract excerpt
AIM: Fragile X syndrome is associated with cognitive deficits in inhibitory control and with abnormal neuronal morphology and development. METHOD: In this study, we used a diffusion tensor imaging (DTI) tractography approach to reconstruct white-matter fibers in the ventral frontostriatal pathway in young males with fragile X syndrome (n=17; mean age 2y 9mo, SD 7mo, range 1y 7mo-3y 10mo), and two age-matched...
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