Diffusion tensor imaging in male premutation carriers of the fragile X mental retardation gene

Abstract excerpt

Older male premutation carriers of the FMR1 gene are associated with the risk of developing a late-onset neurodegenerative disorder, fragile X-associated tremor/ataxia syndrome. Although previous postmortem and in vivo magnetic resonance imaging studies have indicated white matter pathology, the regional selectivity of abnormalities, as well as their relationship with molecular variables of the FMR1 gene, has not...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Advanced Neuroimaging Techniques and Applications
• Share to Genetics and Neurodevelopmental Disorders
• Share to Genomic variations and chromosomal abnormalities