Article
Influence of the fragile X mental retardation (FMR1) gene on the brain and working memory in men with normal FMR1 alleles.
NeuroImage - 15 Jan 2013
Wang Jun Yi, Hessl David, Iwahashi Christine, Cheung Katherine, Schneider Andrea, Hagerman Randi J, Hagerman Paul J, Rivera Susan M
Abstract excerpt
The fragile X mental retardation 1 (FMR1) gene plays an important role in the development and maintenance of neuronal circuits that are essential for cognitive functioning. We explored the functional linkage(s) among lymphocytic FMR1 gene expression, brain structure, and working memory in healthy adult males. We acquired T1-weighted and diffusion tensor imaging from 37 males (18-80 years, mean ± SD= 40.7 ± 17.3...
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