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Article

Distinct KIR/HLA compound genotypes affect the kinetics of human antiviral natural killer cell responses.

The Journal of clinical investigation - 1 Mar 2008

Ahlenstiel Golo, Martin Maureen P, Gao Xiaojiang, Carrington Mary, Rehermann Barbara

Abstract excerpt

Genetic studies suggest a role for killer cell immunoglobulin-like receptor/HLA (KIR/HLA) compound genotypes in the outcome of viral infections, but functional data to explain these epidemiological observations have not been reported. Using an in vitro model of infection with influenza A virus (IAV), we attribute functional differences in human NK cell activity to distinct KIR/HLA genotypes. Multicolor flow...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HLA-C Antigens

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Source

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Identifiers

PMID: 18246204
DOI: 10.1172/JCI32400
PMCID: PMC2214845

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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