Article
Influence of caspases 8 and 9 gene promoter polymorphism on prostate cancer susceptibility and early development of hormone refractory prostate cancer.
BJU international - 1 Feb 2011
Kesarwani Pravin, Mandal Raju K, Maheshwari Ruchir, Mittal Rama Devi
Abstract excerpt
OBJECTIVE: To investigate, by genotyping CASP8 (-652 6N del/ins) and CASP9 (-1263 A > G; -293 19N del/ins), whether inactivation of apoptosis by genetic polymorphism of caspases 8 and 9 play an integral role in the mechanism of cancer development. To investigate the role of these polymorphisms in...
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