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Article

Caspase 9 promoter polymorphisms confer increased susceptibility to breast cancer.

Cancer genetics - 1 Oct 2012

Theodoropoulos George E, Michalopoulos Nikolaos V, Pantou Malena P, Kontogianni Panagiota, Gazouli Maria, Karantanos Theodoros, Lymperi Maria, Zografos George C

Abstract excerpt

Caspases (CASPs), play a crucial role in the development and progression of cancer. We evaluated the association between two polymorphisms (rs4645978 and rs4645981) of the CASP9 gene and the risk of breast cancer (BC). Genotypes and allelic frequencies for the two polymorphisms were determined in 261 patients with breast cancer and 480 healthy controls. Polymerase chain reaction-restriction fragment length...

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Identifiers

PMID: 22981751
DOI: 10.1016/j.cancergen.2012.08.001

Genes

CASP9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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