Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pleural mesothelial cell transformation into myofibroblasts and haptotactic migration in response to TGF-beta1 in vitro.

American journal of physiology. Lung cellular and molecular physiology - 1 Jul 2009

Nasreen Najmunnisa, Mohammed Kamal A, Mubarak Kamal K, Baz Maher A, Akindipe Olufemi A, Fernandez-Bussy Sebastian, Antony Veena B

Abstract excerpt

Idiopathic pulmonary fibrosis (IPF) is a disease of unknown etiology characterized by the development of subpleural foci of myofibroblasts that contribute to the exuberant fibrosis noted in the pulmonary parenchyma. Pleural mesothelial cells (PMC) are metabolically dynamic cells that cover the lung and chest wall as a monolayer and are in intimate proximity to the underlying lung parenchyma. The precise role of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cadherins
Share to Cell Line, Transformed

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Collagen Type I

Share to Cytoskeleton

Share to Mesoderm

Share to Smad2 Protein

Share to Smad4 Protein

Share to Transforming Growth Factor beta1

Source

Open in PubMed Open full text

Identifiers

PMID: 19411308
DOI: 10.1152/ajplung.90587.2008
PMCID: PMC2711818

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pleural mesothelial cell transformation into myofibroblasts and haptotactic migration in response to TGF-beta1 in vitro.PMID 19411308Read ↗

Mechanisms and Therapeutic Potential of Myofibroblast Transformation in Pulmonary FibrosisSemantic proximity Read ↗

TGF-β1 induces human alveolar epithelial to mesenchymal cell transition (EMT)Semantic proximity Read ↗

TGF-beta1 induces progressive pleural scarring and subpleural fibrosis.Semantic proximity Read ↗

Induction of epithelial-mesenchymal transition in alveolar epithelial cells by transforming growth factor-beta1: potential role in idiopathic pulmonary fibrosis.Semantic proximity Read ↗

Cellular Players in Lung FibrosisSemantic proximity Read ↗

Proliferation of pulmonary interstitial fibroblasts is mediated by transforming growth factor-beta1-induced release of extracellular fibroblast growth factor-2 and phosphorylation of p38 MAPK and JNK.Semantic proximity Read ↗

Idiopathic pulmonary fibrosis: an altered fibroblast proliferation linked to cancer biology.Semantic proximity Read ↗

Matrix abnormalities in pulmonary fibrosis.Semantic proximity Read ↗

Sfrp1 inhibits lung fibroblast invasion during transition to injury-induced myofibroblastsSemantic proximity Read ↗

Novel differences in gene expression and functional capabilities of myofibroblast populations in idiopathic pulmonary fibrosisSemantic proximity Read ↗

Hyper-responsiveness of IPF/UIP fibroblasts: interplay between TGFbeta1, IL-13 and CCL2.Semantic proximity Read ↗

Collagen 3D matrices as a model for the study of cell behavior in pulmonary fibrosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.