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Article

Novel differences in gene expression and functional capabilities of myofibroblast populations in idiopathic pulmonary fibrosis

9 Aug 2018

Abstract excerpt

Idiopathic pulmonary fibrosis (IPF), a chronic progressive interstitial pneumonia, is characterized by excessive fibroproliferation. Key effector cells in IPF are myofibroblasts that are recruited from three potential sources: resident fibroblasts, fibrocytes, and epithelial cells. We hypothesized that IPF myofibroblasts from different sources display unique gene expression differences and distinct functional...

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Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30091381
DOI: 10.1152/ajplung.00543.2017

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