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Article

Association of MICA with rheumatoid arthritis independent of known HLA-DRB1 risk alleles in a family-based and a case control study.

Arthritis research & therapy - 1 Jan 2009

Kirsten Holger, Petit-Teixeira Elisabeth, Scholz Markus, Hasenclever Dirk, Hantmann Helene, Heider Dirk, Wagner Ulf, Sack Ulrich, Hugo Teixeira Vitor, Prum Bernard, Burkhardt Jana, Pierlot Céline, Emmrich Frank, Cornelis François, Ahnert Peter

Abstract excerpt

INTRODUCTION: The gene MICA encodes the protein major histocompatibility complex class I polypeptide-related sequence A. It is expressed in synovium of patients with rheumatoid arthritis (RA) and its implication in autoimmunity is discussed. We analyzed the association of genetic variants of MICA with susceptibility to RA. METHODS: Initially, 300 French Caucasian individuals belonging to 100 RA trio families were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 19409079
DOI: 10.1186/ar2683
PMCID: PMC2714103

Genes

MICA

Provenance

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Related research

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Association of MICA with rheumatoid arthritis independent of known HLA-DRB1 risk alleles in a family-based and a case control study.PMID 19409079Read ↗

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