Article
Association study of MICA gene polymorphisms with rheumatoid arthritis susceptibility in south Tunisian population.
International journal of immunogenetics - 1 Dec 2014
Achour Y, Kammoun A, Ben Hamad M, Mahfoudh N, Chaabane S, Marzouk S, Keskes L, Gaddour L, Bahloul Z, Maalej A
Abstract excerpt
The aim of this study was to investigate the role of major histocompatibility complex (MHC) class I chain-related gene A (MICA) polymorphisms, important in natural killer (NK) cell function, in patients with rheumatoid arthritis (RA). A transmembrane (TM) alanine-encoding GCT repeats, termed A4, A5, A5.1, A6 and A9 in the MICA gene, and single-nucleotide polymorphisms (SNPs): the Met129Val polymorphism...
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