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Article

CD226 (DNAM-1) is associated with susceptibility to juvenile idiopathic arthritis.

Annals of the rheumatic diseases - 1 Dec 2015

Reinards T H C M, Albers H M, Brinkman D M C, Kamphuis S S M, van Rossum M A J, Girschick H J, Wouters C, Hoppenreijs E P A H, Saurenmann R K, Hinks A, Ellis J A, Bakker E, Verduijn W, Slagboom P, Huizinga T W J, Toes R E M, Houwing-Duistermaat J J, ten Cate R, Schilham M W

Abstract excerpt

OBJECTIVES: Juvenile idiopathic arthritis (JIA) is considered a complex genetic autoimmune disease. We investigated the association of genetic variants previously implicated in JIA, autoimmunity and/or immunoregulation, with susceptibility to JIA. METHODS: A genetic association study was performed in 639 JIA patients and 1613 healthy controls of northwest European descent. Ninety-three single nucleotide...

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Topics

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Share to Antigens, Differentiation, T-Lymphocyte
Share to Arthritis, Juvenile

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to PTPN22 gene

Share to Genetic Association Studies

Share to Genetic Predisposition to Disease

Share to Genotype

Share to Polymorphism, Genetic

Source

Identifiers

PMID: 25057181
DOI: 10.1136/annrheumdis-2013-205138

Genes

PTPN22
VTCN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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