Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MHC class I chain-related gene B (MICB) is associated with rheumatoid arthritis susceptibility.

Rheumatology (Oxford, England) - 1 Mar 2007

López-Arbesu R, Ballina-García F J, Alperi-López M, López-Soto A, Rodríguez-Rodero S, Martínez-Borra J, López-Vázquez A, Fernández-Morera J L, Riestra-Noriega J L, Queiro-Silva R, Quiñones-Lombraña A, López-Larrea C, González S

Abstract excerpt

OBJECTIVES: Several recent studies have shown that the MHC class III region, located telomeric to HLA-DRB1, contains an additional genetic factor that predisposes to rheumatoid arthritis (RA). In this study, we investigate whether inhibitor of kappaB-like (IkappaBL), MICB or MICA located in the MHC class III region are the second susceptibility gene associated with RA. METHODS: A total of 154 healthy controls and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptor Proteins, Signal Transducing
Share to Arthritis, Rheumatoid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Histocompatibility Antigens Class I

Share to Histocompatibility Antigens Class II

Share to Histocompatibility Testing

Share to HLA-DR Antigens

Share to HLA-DRB1 Chains

Share to Linkage Disequilibrium

Source

Identifiers

PMID: 17003176
DOI: 10.1093/rheumatology/kel331

Genes

MICB
MICA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MHC class I chain-related gene B (MICB) is associated with rheumatoid arthritis susceptibility.PMID 17003176Read ↗

MICB*002 and MICB*014 protect against rheumatoid arthritis, whereas MICA*009 and MICA*A6 are associated with rheumatoid arthritis in a Hainan Han Chinese population.Semantic proximity Read ↗

Association of MICA with rheumatoid arthritis independent of known HLA-DRB1 risk alleles in a family-based and a case control study.Semantic proximity Read ↗

Genetic association of the major histocompatibility complex with rheumatoid arthritis implicates two non-DRB1 loci.Semantic proximity Read ↗

Associative role of HLA-DRB1 SNP genotypes as risk factors for susceptibility and severity of rheumatoid arthritis: A North-east Indian population-based study.Semantic proximity Read ↗

Identification of I kappa BL as the second major histocompatibility complex-linked susceptibility locus for rheumatoid arthritis.Semantic proximity Read ↗

A second susceptibility gene for developing rheumatoid arthritis in the human MHC is localized within a 70-kb interval telomeric of the TNF genes in the HLA class III region.Semantic proximity Read ↗

Genetic influence of the nonclassical major histocompatibility complex class I molecule MICB in multiple sclerosis susceptibility.Semantic proximity Read ↗

IRAK1 Gene Polymorphism in Rheumatoid Arthritis.Semantic proximity Read ↗

HLA-C alleles confer risk for anti-citrullinated peptide antibody-positive rheumatoid arthritis independent of HLA-DRB1 alleles.Semantic proximity Read ↗

Analysis of single-nucleotide polymorphisms in Japanese rheumatoid arthritis patients shows additional susceptibility markers besides the classic shared epitope susceptibility sequences.Semantic proximity Read ↗

Association of HLA-DQB1 polymorphisms with rheumatoid arthritis: a meta-analysis.Semantic proximity Read ↗

HLA haplotypes and susceptibility to rheumatoid arthritis. More than class II genes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.