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Article

Association of genetic variation in mitotic kinases with breast cancer risk.

Breast cancer research and treatment - 1 Jan 2010

Wang Xianshu, Fredericksen Zachary S, Vierkant Robert A, Kosel Matthew L, Pankratz V Shane, Cerhan James R, Justenhoven Christina, Brauch Hiltrud, Olson Janet E, Couch Fergus J

Abstract excerpt

An RNAi-based functional screening of mitotic kinases in Drosophila recently identified a number of members of the kinome that are required for normal cell division. Depletion of these kinases resulted in a number of different mitotic abnormalities including spindle malformation, chromosome mis-segregation, centrosome amplification and failure of cytokinesis (Bettencourt-Dias et al. in Nature 432:980-987, 2004)....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19404734
DOI: 10.1007/s10549-009-0404-3
PMCID: PMC2796295

Genes

FYN
MAST2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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