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Article

Variation in genes required for normal mitosis and risk of breast cancer.

Breast cancer research and treatment - 1 Jan 2010

Olson J E, Wang X, Goode E L, Pankratz V S, Fredericksen Z S, Vierkant R A, Pharoah P D P, Cerhan J R, Couch F J

Abstract excerpt

The down-regulation of genes involved in normal cell division can cause aberrant mitoses and increased cell death. Surviving cells exhibit aneuploidy and/or polyploidy. Since mitotic disruption has been linked with tumor development and progression, alterations in the expression or activity of these mitotic regulators may contribute to breast tumor formation. We evaluated associations between common inherited...

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Identifiers

PMID: 19377877
DOI: 10.1007/s10549-009-0386-1
PMCID: PMC2818059

Genes

SART1
CDC16
MFAP1
SNW1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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