Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effects of tumor-associated mutations in the p53 tetramerization domain on oligomerization state and transcriptional activity.

Advances in experimental medicine and biology - 1 Jan 2009

Kamada Rui, Terai Tomoko, Nomura Takao, Chuman Yoshiro, Imagawa Toshiaki, Sakaguchi Kazuyasu

Abstract excerpt

No abstract is available from the source.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Biopolymers
Share to Models, Molecular
Share to Molecular Sequence Data

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to Thermodynamics

Share to Transcription, Genetic

Share to Tumor Suppressor Protein p53

Source

Identifiers

PMID: 19400316
DOI: 10.1007/978-0-387-73657-0_249

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 24 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effects of tumor-associated mutations in the p53 tetramerization domain on oligomerization state and transcriptional activity.PMID 19400316Read ↗

The role of tetramerization in p53 function.Semantic proximity Read ↗

Cancer-associated p53 tetramerization domain mutants: quantitative analysis reveals a low threshold for tumor suppressor inactivation.Semantic proximity Read ↗

The Status of p53 Oligomeric and Aggregation States in CancerSemantic proximity Read ↗

p53 oligomerization status modulates cell fate decisions between growth, arrest and apoptosisSemantic proximity Read ↗

Characterization of p53 mutants identified in human tumors with a missense mutation in the tetramerization domain.Semantic proximity Read ↗

Structural Basis of Mutation-Dependent p53 Tetramerization Deficiency.Semantic proximity Read ↗

Structure and functionality of a designed p53 dimer.Semantic proximity Read ↗

Wild-type and cancer-related p53 proteins are preferentially degraded by MDM2 as dimers rather than tetramers.Semantic proximity Read ↗

Structural Basis of Mutation-Dependent p53 Tetramerization DeficiencySemantic proximity Read ↗

Unfolding, aggregation, and amyloid formation by the tetramerization domain from mutant p53 associated with lung cancer.Semantic proximity Read ↗

New insights into p53 function from structural studies.Semantic proximity Read ↗

Conformational shifts propagate from the oligomerization domain of p53 to its tetrameric DNA binding domain and restore DNA binding to select p53 mutants.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.