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Article

Association of the DRD2 and DRD3 polymorphisms with response to pramipexole in Parkinson's disease patients.

European journal of clinical pharmacology - 1 Jul 2009

Liu Ying-Zi, Tang Bei-Sha, Yan Xin-Xiang, Liu Jie, Ouyang Dong-Sheng, Nie Li-Nuo, Fan Lan, Li Zhi, Ji Wei, Hu Dong-Li, Wang Dan, Zhou Hong-Hao

Abstract excerpt

OBJECTIVE: To evaluate the impact of the DRD2 TaqIA and DRD3 Ser9Gly polymorphisms on the efficacy of pramipexole in treating patients with Parkinson's disease (PD). METHODS: Thirty patients with PD prospectively received pramipexole 0.25 mg three times daily for 2 months. Unified Parkinson Disease Rating Scale (UPDRS) assessments were conducted at baseline and 2 months after treatment initiation. Improvement by...

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Source

Identifiers

PMID: 19396436
DOI: 10.1007/s00228-009-0658-z

Genes

DRD3
DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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