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Article

HLA-DRA is associated with Parkinson's disease in Iranian population.

International journal of immunogenetics - 1 Dec 2014

Jamshidi J, Movafagh A, Emamalizadeh B, Zare Bidoki A, Manafi A, Ghasemi Firouzabadi S, Shahidi G-A, Kazeminasab S, Petramfar P, Fazeli A, Motallebi M, Mortazavi-Tabatabaei S A, Kowsari A, Jafarian Z, Darvish H

Abstract excerpt

The rs3129882, a noncoding variant in HLA-DR, was found to be associated with Parkinson's disease (PD) using several genome-wide association studies. The aim of this replication study was to explore the relationship between this variant and PD in Iranian population. Genomic DNA was extracted from peripheral blood samples, and the rs3129882 SNP was genotyped using a PCR-RFLP method in 520 PD patients and 520...

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PMID: 25319953
DOI: 10.1111/iji.12151

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