The dopamine D2 receptor gene is a susceptibility locus for Parkinson's disease.

doi:10.1002/1531-8257(200001)15:1<120::aid-mds1019>3.0.co;2-s

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Article

The dopamine D2 receptor gene is a susceptibility locus for Parkinson's disease.

Movement disorders : official journal of the Movement Disorder Society - 1 Jan 2000

Oliveri R L, Annesi G, Zappia M, Civitelli D, De Marco E V, Pasqua A A, Annesi F, Spadafora P, Gambardella A, Nicoletti G, Branca D, Caracciolo M, Aguglia U, Quattrone A

Abstract excerpt

The dopamine D2 receptor (DRD2) gene has been proposed as a candidate gene underlying several psychiatric and neurologic disorders. The aim of the present study was to examine if selected polymorphisms in the DRD2 gene are associated with Parkinson's disease (PD). We determined the allelic frequencies for four polymorphisms located in the DRD2 gene in a sample of 135 patients with PD and 202 normal control...

Topics

Aged
Alleles
Chromosome Mapping
Female
Gene Frequency
Genetic Predisposition to Disease
Genotype
Humans
Italy
Linkage Disequilibrium

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Parkinson Disease

Polymorphism, Genetic

Prospective Studies

Receptors, Dopamine D2

Risk

Source

Open in PubMed

Identifiers

PMID: 10634251
DOI: 10.1002/1531-8257(200001)15:1<120::aid-mds1019>3.0.co;2-s

Genes

DRD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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