Article
Association of dopamine receptor D1 (DRD1) polymorphisms with risperidone treatment response in Chinese schizophrenia patients.
Neuroscience letters - 1 Jan 2015
Huo Ran, Wei Zhiyun, Xiong Yuyu, Jiang Jie, Liu Yichen, Yan Yucai, Shi Jiajun, Li Wenqiang, Cui Donghong, Xing Qinghe, He Lin, Qin Shengying
Abstract excerpt
Evidence suggests that dopamine receptor D1 (DRD1) may be involved in the pathophysiology of schizophrenia and the pharmacodynamics of antipsychotics. We conducted a comprehensive pharmacogenomics study to investigate the association of genetic polymorphisms in DRD1 with treatment response to risperidone. Two independent cohorts of Han Chinese schizophrenic patients (n = 185) from two different geographic areas...
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