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Article

Comparing the influence of dopamine D₂ polymorphisms and plasma drug concentrations on the clinical response to risperidone.

Journal of clinical psychopharmacology - 1 Oct 2011

Yasui-Furukori Norio, Tsuchimine Shoko, Saito Manabu, Nakagami Taku, Sugawara Norio, Fujii Akira, Kaneko Sunao

Abstract excerpt

Although several studies have reported that dopamine D₂ receptor (DRD2) polymorphisms affect the therapeutic efficacy of antipsychotics, other studies have suggested that the plasma drug concentration is related to the clinical response. Currently, there are no definitive data regarding which factor has greater clinical significance. Sixty patients with acute exacerbations of schizophrenia received 6 mg/d of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21869689
DOI: 10.1097/JCP.0b013e31822c09a7

Genes

DRD2

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