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Article

The catechol-O-methyltransferase and monoamine oxidase B polymorphisms and levodopa therapy in the Iranian patients with sporadic Parkinson's disease.

Acta neurobiologiae experimentalis - 1 Jan 2012

Torkaman-Boutorabi Anahita, Shahidi Gholam Ali, Choopani Samira, Rezvani Mohammad, Pourkosary Kosar, Golkar Majid, Zarrindast Mohammad-Reza

Abstract excerpt

Parkinson's disease (PD) patients vary widely in their response to levodopa treatment, and this may be partially genetic in origin. Recent studies suggest that catechol-O-methyltransferase (COMT), G1947A and monoamine oxidase B (MAOB), A644G polymorphisms might influence the risk and treatment of PD. Herein, we aimed to test the possible influence of MAOB and COMT genetic polymorphisms on the effective daily dose...

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Identifiers

PMID: 23093014
DOI: 10.55782/ane-2012-1900

Genes

COMT
MAOB

Variants

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The catechol-O-methyltransferase and monoamine oxidase B polymorphisms and levodopa therapy in the Iranian patients with sporadic Parkinson's disease.PMID 23093014Read ↗

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