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Article

Genetic locus on mouse chromosome 7 controls elevated heart rate.

Physiological genomics - 3 Jul 2012

Smolock Elaine M, Ilyushkina Irina A, Ghazalpour Anatole, Gerloff Janice, Murashev Arkady N, Lusis Aldons J, Korshunov Vyacheslav A

Abstract excerpt

Elevated heart rate (HR) is a risk factor for cardiovascular diseases. The goal of the study was to map HR trait in mice using quantitative trait locus (QTL) analysis followed by genome-wide association (GWA) analysis. The first approach provides mapping power and the second increases genome resolution. QTL analyses were performed in a C3HeB×SJL backcross. HR and systolic blood pressure (SBP) were measured by the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22589454
DOI: 10.1152/physiolgenomics.00041.2012
PMCID: PMC3426427

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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