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Article

Polymorphisms in the interleukin-22 receptor alpha-1 gene are associated with severe chronic rhinosinusitis.

Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery - 1 May 2009

Endam Leandra Mfuna, Bossé Yohan, Filali-Mouhim Abdelali, Cormier Chantale, Boisvert Pierre, Boulet Louis-Philippe, Hudson Thomas J, Desrosiers Martin

Abstract excerpt

RATIONALE: Stimulation of interleukin-22 receptor alpha-1 (IL22RA1) was reported to increase the innate immune responses in inflammatory diseases. Moreover, a reduced level of IL22RA1 was found in patients with recalcitrant CRS with nasal polyps. OBJECTIVE: To explore association between single nucleotide polymorphisms (SNPs) in IL22RA1 and severe CRS. METHODS: We extracted DNA from 206 cases with severe CRS and...

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Identifiers

PMID: 19393422
DOI: 10.1016/j.otohns.2008.12.058

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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