Chronic Rhinosinusitis Patients Show Accumulation of Genetic Variants in PARS2.

doi:10.1371/journal.pone.0158202

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Article

Chronic Rhinosinusitis Patients Show Accumulation of Genetic Variants in PARS2.

PloS one - 1 Jan 2016

Henmyr Viktor, Lind-Halldén Christina, Halldén Christer, Säll Torbjörn, Carlberg Daniel, Bachert Claus, Cardell Lars-Olaf

Abstract excerpt

Genetic studies of chronic rhinosinusitis (CRS) have identified a total of 53 CRS-associated SNPs that were subsequently evaluated for their reproducibility in a recent study. The rs2873551 SNP in linkage disequilibrium with PARS2 showed the strongest association signal. The present study aims to comprehensively screen for rare variants in PARS2 and evaluate for accumulation of such variants in CRS-patients....

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PMID: 27348859
DOI: 10.1371/journal.pone.0158202
PMCID: PMC4922623

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PARS2

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