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Article

A polymorphism of interleukin-22 receptor alpha-1 is associated with the development of childhood IgA nephropathy.

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research - 1 Oct 2013

Suh Jin-Soon, Cho Seong H, Chung Joo-Ho, Moon Ahrim, Park Yong-Koo, Cho Byoung-Soo

Abstract excerpt

Recent studies suggest that dysregulated innate immunity plays an important role in the pathogenesis of immunoglobulin A nephropathy (IgAN). The interleukin-20 subfamily and its receptor, interleukin-22 receptor alpha-1 (IL-22R1), were recently identified as immunomodulators in human diseases, acting as mediators of mucosal host defense. However, the potential role of IL-22R1 in the pathogenesis of IgAN has not...

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Identifiers

PMID: 23659670
DOI: 10.1089/jir.2012.0097
PMCID: PMC3793651

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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