Article
Evidence of association of interleukin-1 receptor-like 1 gene polymorphisms with chronic rhinosinusitis.
American journal of rhinology & allergy - 1 Jan 2000
Castano Roberto, Bossé Yohan, Endam Leandra Mfuna, Desrosiers Martin
Abstract excerpt
BACKGROUND: Chronic rhinosinusitis (CRS) is a common complex respiratory disease, with a potential genetic component to its development. The protein encoded by the Interleukin-1 receptor-like 1 (IL1RL1) gene is an important effector molecule of T-helper type 2 responses and may potentially be involved in the persistent inflammatory process observed in CRS. We investigated whether certain polymorphisms in the...
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