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Article

Polymorphisms in the nitric oxide synthase 1 gene are associated with severe chronic rhinosinusitis.

American journal of rhinology & allergy - 1 Jan 2000

Zhang Yuan, Endam Leandra Mfuna, Filali-Mouhim Abdelali, Bossé Yohan, Castano Roberto, Desrosiers Martin

Abstract excerpt

BACKGROUND: Nitric oxide (NO), is a biological messenger molecule and a component of innate immunity, with important roles in the regulation of inflammation and in defense against bacterial biofilms. Polymorphisms in genes regulating NO production have the potential for a role in the development of chronic rhinosinusitis (CRS). The purpose of this study was to determine whether polymorphisms in genes regulating...

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Source

Identifiers

PMID: 21679499
DOI: 10.2500/ajra.2011.25.3588

Genes

NOS1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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