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Article

Assessment of Toll-like receptor 2 gene polymorphisms in severe chronic rhinosinusitis.

Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale - 1 Aug 2008

Tewfik Marc A, Bossé Yohan, Hudson Thomas J, Vallée-Smejda Sophie, Al-Shemari Hasan, Desrosiers Martin

Abstract excerpt

BACKGROUND: Chronic rhinosinusitis (CRS) is believed to reflect an inflammatory response of the sinonasal mucosa to bacteria and/or fungi. Staphylococcus aureus, a gram-positive organism, is frequently implicated. Toll-like receptor 2 (TLR2) is involved in innate immunity, recognizing gram-positive organisms via detection of bacterial lipopeptides. As a poor response to sinus surgery has been associated with...

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Source

Identifiers

PMID: 19128592

Genes

TLR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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